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MAY 16, 2025

USPSTF: Updated Guidance for Syphilis Screening During Pregnancy


Originally published by our sister publication Infectious Disease Special Edition

By Meaghan Lee Callaghan

The  U.S. Preventive Services Task Force (USPSTF) is continuing to recommend early, universal syphilis screening during pregnancy. 

The new guidance, a restatement of its 2018 guideline, comes at a time when syphilis cases remain high in the United States. That also includes congenital syphilis, which caused 279 stillbirths or neonatal/infant deaths in 2023—the highest number