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FEBRUARY 13, 2023

Ketogenic Diet Poses USP <800> Challenge For Anti-Seizure Meds

By Dan Hurley
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Jon A. Cokley, PharmD

LAS VEGAS—Use of the ketogenic diet for children whose epilepsy does not respond to anti-seizure medications (ASMs) alone poses unique safety challenges, but pharmacists can take steps to protect themselves and their patients under standards established by USP General Chapter <800>.

Challenges exist not only because of the ketogenic diet itself but the need to avoid carbohydrates in the ASMs and concomitant medications required by these pediatric