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JANUARY 30, 2019

C. diff Testing Shouldn’t Be Based on Lab Test Alone

By Ethan Covey

Although toxin-positive Clostridioides difficile (formerly Clostridium difficile) infection (CDI) is more severe and more likely to recur than that detected only by nucleic acid amplification testing (NAAT), there are no differences in CDI-related complications and mortality rates between the two, according to a new study (Clin Infect Dis 2019 Jan 7. ciz009. https://doi.org/10.1093/cid/ciz009).

“Our findings highlight that the diagnosis of CDI should not be based on a