This story was updated on Feb. 26.
By Marcus A. Banks
Recent literature shows that cefepime may be emerging as a preferred empiric therapy for critically ill patients with sepsis, compared with piperacillin-tazobactam (PIP/TAZO); that a prolonged infusion of beta-lactam antibiotics to treat critically ill sepsis may decrease mortality; and that de-escalation of broad-spectrum antibiotics used to treat sepsis could reduce the development of antibiotic-resistant bacteria.
Susan Smith, PharmD, BCPS,