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FEBRUARY 22, 2023

Mpox and Severe HIV—A Toxic Relationship


Originally published by our sister publication Infectious Disease Special Edition

By Marie Rosenthal, MS

A severe, necrotizing form of mpox with a high mortality rate among people with HIV whose CD4 count was less than 200 cells/m3 was described at CROI 2023, held in Seattle (presentation 173).

“The first key finding that we have is there was a very clear relationship between CD4 count, viral load and outcomes,” said Chloe Orkin, MBBCH, MSc, a professor of HIV medicine in the Center