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JANUARY 29, 2023

Preemptive Levetiracetam May Reduce Pain and Need for Fentanyl After Surgery


Originally published by our sister publication Pain Medicine News

By Myles Starr

The preemptive use of levetiracetam (LEV), in conjunction with opioids, as an analgesic is supported by findings of a recent study.

The double-blind, randomized, placebo-controlled study included 42 participants (18-60 years of age; 22 men and 20 women) divided into a control or LEV group (Cureus 2023;15[1]:e33281). Patients with a history of substance abuse, hypersensitivity to LEV, or “significant respiratory,