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AUGUST 27, 2019

FDA Approves Rinvoq for Moderate to Severe RA

By PPN News Staff

The FDA has approved upadacitinib (Rinvoq, AbbVie), a once-daily oral Janus kinase (JAK) inhibitor, for the treatment of adults with moderately to severely active rheumatoid arthritis (RA) who have had an inadequate response or intolerance to methotrexate (MTX-IR).

The FDA approval of upadacitinib is supported by data from the SELECT program, one of the largest registrational phase 3 programs in RA, with approximately 4,400 patients evaluated across all treatment arms in five