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JANUARY 21, 2025

FDA Approves Lumakras With Vectibix for KRAS G12C–Mutated Colorectal Cancer


Originally published by our sister publication Clinical Oncology News

By Clinical Oncology News Staff

The FDA has approved sotorasib (Lumakras, Amgen) with panitumumab (Vectibix, Amgen) for adult patients with KRAS G12C–mutated metastatic colorectal cancer (mCRC), as determined by an FDA-approved test, who have received prior fluoropyrimidine-, oxaliplatin- and irinotecan-based chemotherapy.

The FDA also approved the therascreen KRAS RGQ PCR Kit (QIAGEN GmbH) as a companion diagnostic device