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AUGUST 21, 2023

FDA Approves Veopoz for CHAPLE Disease

By PPN Staff

The FDA approved pozelimab-bbfg (Veopoz, Regeneron) as the first treatment for CD55-deficient protein-losing enteropathy, also known as complement hyperactivation, angiopathic thrombosis and protein-losing enteropathy, or CHAPLE disease. The complement inhibitor was granted approval for adult and pediatric patients aged 1 year and older. 

Fewer than 100 patients have been diagnosed with CHAPLE disease worldwide, according to the FDA. This extremely rare disease, which stems from