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MAY 29, 2019

FDA Approves Alpelisib, First PI3K Inhibitor for Breast Cancer

By PPN News Staff

The FDA approved alpelisib (Piqray, Novartis) tablets, to be used with the FDA-approved endocrine therapy fulvestrant (Faslodex, AstraZeneca) to treat postmenopausal women, and men, with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, PIK3CA-mutated, advanced or metastatic breast cancer (as detected by an FDA-approved test) following progression on or after an endocrine-based regimen.

The FDA also approved the companion diagnostic test,