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MAY 22, 2025

VRBPAC Recommends New SARS-CoV-2 Strain for Updated COVID-19 Vaccines


Originally published by our sister publication Infectious Disease Special Edition

By Marie Rosenthal, MS

In a unanimous decision, the FDA’s Vaccines and Related Biological Products Advisory Committee recommended the JN.1 and/or a specific JN.1-lineage strain should be used in the 2025-2026 formula for updated COVID-19 vaccines. 

As SARS-CoV-2 circulates, it has been mutating with one strain after another becoming dominant. The delta strain became dominant in India in 2020, but by around