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JANUARY 10, 2023

Concerns of Evusheld Lacking Protection Against Omicron XBB.1.5


Originally published by our sister publication Infectious Disease Special Edition

The FDA does not expect tixagevimab co-packaged with cilgavimab (TIX+CIL) (Evusheld, AstraZeneca) to have the ability to neutralize XBB.1.5, a new emerging omicron subvariant, the agency said.

The CDC estimates XBB.1.5 to be responsible for nearly 30% of variant circulation in the United States.

In October, the FDA released an update adding important information to the authorized Fact Sheets for Evusheld to inform