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NOVEMBER 21, 2024

CNS Involvement in Immunocompromised Shingles Patients: Don’t Miss the Subtle Signs

By Gina Shaw

A retrospective case series study of immunocompromised patients with active herpes zoster infections who presented for care with skin lesions and subtle neurologic manifestations found that 100% had a positive test for the virus in their cerebrospinal fluid (CSF), reported the study’s authors at IDWeek 2024, in Los Angeles (poster P-910).

“Subtle signs of VZV [varicella-zoster virus] infection of the CNS [central nervous system] can be misleading and easily mistaken for