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MARCH 15, 2023

Study Confirms B12 Deficiency Risk From Metformin

By Karen Blum

SAN FRANCISCO—Long-term use of metformin is associated with a significantly increased risk for vitamin B12 deficiency, suggesting there may be value in screening and monitoring levels of the vitamin in these patients to determine if supplementation is needed, researchers said at the 2022 ACCP Global Conference on Clinical Pharmacy (poster #Sat-5).

The study included 327,000 diverse people from across the country, about 6,221 of whom were reported as having a diagnosis of type