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AUGUST 30, 2018

FDA Approves Delstrigo and Pifeltro for HIV Treatment

By PPN News Staff

The FDA approved Merck’s two doravirine-based HIV-1 medicines. 

Delstrigo, a once-daily fixed-dose combination tablet of doravirine (DOR, 100 mg), lamivudine (3TC, 300 mg) and tenofovir disoproxil fumarate (TDF, 300 mg); and Pifeltro (doravirine alone, 100 mg), a new non-nucleoside reverse transcriptase inhibitor (NNRTI), will be administered in combination with other antiretroviral drugs. 

Both DOR/3TC/TDF and DOR alone are indicated for the treatment of HIV-1