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MAY 18, 2016

Some Antibiotics May Worsen GVHD in Transplant Patients

 
Some broad-spectrum antibiotics that disrupt the gut microbiome may raise the risk for complications after hematopoietic stem cell transplantation, according to a new study evaluating data from more than 850 transplant patients, as well as from mice (Sci Transl Med 2016 May 18. [Epub ahead of print]).
 
The findings suggest that selecting antibiotics that spare beneficial bacteria may help protect against graft-versus-host disease (GVHD), which occurs when