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FEBRUARY 12, 2018

Older Patients With Epilepsy Have High Risk for PK Interactions

By Nikki Kean

Up to one-third of older patients with epilepsy receive a combination of antiepileptic drugs (AEDs) and non-epilepsy medications that could cause potentially dangerous pharmacokinetic (PK) interactions, according to a new study.

In addition, one in five older patients with new-onset epilepsy received a drug combination that altered the effect of the AED and potentially could cause toxicity, noted the authors, led by Edward Faught, MD, of the Department of Neurology at Emory