CHRISTINA I. HEROLD, MD CAREY K. ANDERS, MD KIMBERLY L. BLACKWELL, MD
APRIL, 2009

Venous thromboembolism (VTE), comprised of deep vein thrombosis (DVT) and pulmonary embolism (PE), is a major cause of death, disability, and economic burden worldwide. VTE afflicts millions of individuals and accounts for several hundred thousand deaths annually in the United States.
FEBRUARY, 2009

ROBERT P. RAPP, PHARMD, FCCP
CRAIG MARTIN, PHARMD
OCTOBER, 2008

INSTITUTE FOR SAFE MEDICATION PRACTICES
OCTOBER, 2008

KAREN FIUMARA, PHARMD
MATTHEW MACHADO, PHARMD
JOHN FANIKOS, RPH
OCTOBER, 2008

With an estimated 182,460 new cases and 40,480 related deaths in 2008, breast cancer remains the most common malignancy among US women and the second most lethal. During the 1980s, annual increases in the rate of breast cancer of approximately 3.7% were largely attributed to the widespread adoption of screening mammography.
OCTOBER, 2008

Colorectal cancer is the third leading cause of cancer deaths in men and women in the United States, with an estimated total of 49,960 deaths in 2008. The high number of deaths can be attributed to the inability to achieve cures in a substantial number of patients with metastatic disease.
AUGUST, 2008

For patients with metastatic breast cancer, the goal of therapy is to maximize quality of life while palliating cancer-related symptoms. Many factors must be considered when treatment strategies are selected in this setting, including type and timing of prior therapy; hormonal (estrogen receptor [ER] and progesterone receptor [PR]) status; ERBB2 (formerly HER2/neu) status; location and extent of disease; and patient characteristics, such as age and comorbidities.
MARCH, 2008